PubMed COVID-19 Clinical Care
381 - 390 of 5066 results found
Antiviral fibrils of self-assembled peptides with tunable compositions
Description
The lasting threat of viral pandemics necessitates the development of tailorable first-response antivirals with specific but adaptive architectures for treatment of novel viral infections. Here, such an antiviral platform has been developed based on
Assessing the heterogeneity of the impact of COVID-19 incidence on all-cause excess mortality among healthcare districts in Lombardy, Italy, to evaluate the local response to the pandemic: an ecological study
Description
CONCLUSIONS: The homogeneous effect of the COVID-19 spread on the excess mortality in the Lombardy districts suggests that, despite the unprecedented conditions, the pandemic reactions did not result in health disparities in the region.
An Enzyme-Cleavable Solubilizing-Tag Facilitates the Chemical Synthesis of Mirror-Image Proteins
Description
Mirror-image proteins (D-proteins) are useful in biomedical research for purposes such as mirror-image screening for D-peptide drug discovery, but the chemical synthesis of many D-proteins is often low yielding due to the poor solubility or
A novel method leveraging time series data to improve subphenotyping and application in critically ill patients with COVID-19
Description
Computational subphenotyping, a data-driven approach to understanding disease subtypes, is a prominent topic in medical research. Numerous ongoing studies are dedicated to developing advanced computational subphenotyping methods for cross-sectional
Axillary Lymphadenopathy after COVID-19 Vaccination: Follow-up for Enlarged Lymph Nodes on MR Imaging
Description
CONCLUSION: The enlarged axillary lymph nodes decreased both in size and in signal intensity on T2-weighted images of follow-up MRI. The ADC remained unchanged. Our findings may provide important information to establish evidence-based guidelines for
Arbidol attenuates liver fibrosis and activation of hepatic stellate cells by blocking TGF-β1 signaling
Description
Chronic liver diseases (CLD) impact over 800 million people globally, causing about 2 million deaths annually. Arbidol (ARB), an indole-derivative used to treat influenza virus infection, was extensively used during COVID-19 pandemic in China. In
Association of soluble PD-L1 and NLR combination with 1-Year mortality in patients with COVID-19
Description
CONCLUSION: The combination of two immune-mediated markers (sPD-L1 and NLR), which reflect the systemic inflammatory balance of activation and exhaustion, can complement each other and improve the assessment of the risk of death in patients with
A machine learning approach to identify groups of patients with hematological malignant disorders
Description
CONCLUSIONS: The methodology successfully identified four separate patient clusters using Machine Learning and Explainable AI (XAI). We then analyzed each cluster based on the percentage of HM patients who generated antibodies after COVID-19