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PubMed COVID-19 Clinical Care

4651 - 4660 of 5066 results found

All-atom simulations of the trimeric spike protein of SARS-CoV-2 in aqueous medium: Nature of interactions, conformational stability and free energy diagrams for conformational transition of the protein

Date
Friday, March 31, 2023 - 4:00 AM
Description
The spike protein of SARS-CoV-2 exists in two major conformational states, namely the 'open' and 'closed' states which are also known as the 'up' and 'down' states, respectively. In its open state, the receptor binding domain (RBD) of the protein is

Assessing the generation of tissue resident memory T cells by vaccines

Date
Friday, March 31, 2023 - 4:00 AM
Description
Vaccines have been a hugely successful public health intervention, virtually eliminating many once common diseases of childhood. However, they have had less success in controlling endemic pathogens including Mycobacterium tuberculosis, herpesviruses