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Research
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PubMed COVID-19 Clinical Care

1201 - 1210 of 2171 results found

Divergent adaptive immune responses define two types of long COVID

Date
Thursday, August 10, 2023 - 4:00 AM
Description
CONCLUSIONS: These findings provide evidence for two major types of antiviral immune responses in long COVID. Seropositive patients showed coordinated cellular and humoral responses at least as high as those of recovered patients. In contrast, ELISA

Design of VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1): A double-blind, randomized placebo-controlled trial of COVID-19 convalescent plasma in hospitalized patients with early respiratory compromise

Date
Thursday, August 10, 2023 - 4:00 AM
Description
CONCLUSIONS: VA CURES-1 was a large multi-site trial designed to provide conclusive information about the efficacy of CCP in well-characterized patients at risk for progression of COVID-19. It utilized a rigorous study design with relevant initial

Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication

Date
Thursday, August 10, 2023 - 4:00 AM
Description
For RNA viruses, RNA helicases have long been recognized to play critical roles during virus replication cycles, facilitating proper folding and replication of viral RNAs, therefore representing an ideal target for drug discovery. SARS-CoV-2 helicase

Donor-derived infections in solid organ transplant recipients

Date
Wednesday, August 09, 2023 - 4:00 AM
Description
PURPOSE OF REVIEW: The potential for transmission of donor-derived infections (DDIs) is impossible to eliminate, but a thoughtful and systematic approach to donor evaluation can mitigate the risk. Prevention is a key issue and clinicians must