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PubMed COVID-19 Clinical Care

2031 - 2040 of 3602 results found

Evolutionary safety of lethal mutagenesis driven by antiviral treatment

Date
Tuesday, August 08, 2023 - 4:00 AM
Description
Nucleoside analogs are a major class of antiviral drugs. Some act by increasing the viral mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however, may lead to an evolutionary safety concern. We define evolutionary

Excess iron aggravates the severity of COVID-19 infection

Date
Tuesday, August 08, 2023 - 4:00 AM
Description
Coronavirus disease-19 (COVID-19) can induce severe inflammation of the lungs and respiratory system. Severe COVID-19 is frequently associated with hyper inflammation and hyper-ferritinemia. High iron levels are known to trigger pro-inflammatory