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PubMed COVID-19 Clinical Care

2331 - 2340 of 3558 results found

Immunological imprinting of humoral immunity to SARS-CoV-2 in children

Date
Thursday, June 29, 2023 - 4:00 AM
Description
Omicron variants of SARS-CoV-2 are globally dominant and infection rates are very high in children. We measure immune responses following Omicron BA.1/2 infection in children aged 6-14 years and relate this to prior and subsequent SARS-CoV-2

Increased vaccine sensitivity of an emerging SARS-CoV-2 variant

Date
Thursday, June 29, 2023 - 4:00 AM
Description
Host immune responses are a key source of selective pressure driving pathogen evolution. Emergence of many SARS-CoV-2 lineages has been associated with enhancements in their ability to evade population immunity resulting from both vaccination and

Immune thrombocytopenia in the setting of acute SARS-CoV-2 infection

Date
Thursday, June 29, 2023 - 4:00 AM
Description
Immune thrombocytopenia (ITP) is an immune-mediated event, characterised by the destruction of platelets by autoantibodies resulting in isolated thrombocytopaenia (platelets <100 x10⁹/L). In children, most cases are preceded by a viral infection. Cases of ITP in the setting of SARS-CoV-2 infection have been described. We describe a previously healthy boy, who presented with an extensive frontal and periorbital haematoma, petechial rash on the trunk and coryza. He had suffered a minor head...