PubMed COVID-19 Clinical Care

BACKGROUND: The WHO priority zoonotic pathogen MERS-CoV has a high case fatality rate in humans and circulates in camels worldwide.

The work presents a library of piperine derivatives as potential inhibitors of the main protease protein (Mpro) functionality using Docking Studies, Molecular Dynamics (MD) Simulations and Absolute Binding Free-Energy calculations. 342 ligands were

Internet- or web-based research is rapidly increasing, offering multiple benefits for researchers. However, various challenges in web-based data collection have been illustrated in prior research, particularly since the onset of the COVID-19 pandemic

CONCLUSION: Issues such as increased workload associated with COVID-19 restrictions engendered mental health problems among BAME care workers, however, the workload only further increased during the pandemic, but the health and social care sector was

CONCLUSION: In this study, we identify potent molecules that exhibit interactions with catalytical dyad HIS41 and CYS145 amino acids and unravel Coumarin-EM04 exhibited ΔG(bind) higher than Remdesivir against Mpro and thus may serve better antiviral

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CONCLUSION: These findings have implications not only for the design of social distancing rules but also for efforts to ensure vaccine uptake. Governments need to consider how to harness moral, self-interested, and social motivation to promote

The use of extracorporeal membrane oxygenation (ECMO) is discussed to improve patients' outcome in severe COVID-19 with respiratory failure, but data on ECMO remains controversial. The aim of the study was to determine the characteristics of patients

Chest X-rays (CXR) are the most commonly used imaging methodology in radiology to diagnose pulmonary diseases with close to 2 billion CXRs taken every year. The recent upsurge of COVID-19 and its variants accompanied by pneumonia and tuberculosis can

Because of the pandemic, face masks have become ubiquitous in social interactions, but it remains unclear how face masks influence the ability to discriminate between truthful and deceptive statements. The current study manipulated the presence of