PubMed COVID-19 Clinical Care

Single-span oligomeric α-helical transmembrane proteins are common in virus ion channels, which are targets of antiviral drugs. Knowledge about the high-resolution structures of these oligomeric α-helical bundles is so far scarce. Structure

Molnupiravir (MOV) was introduced in Israel in January 2022 during the SARS-CoV-2 Omicron surge for high-risk patients contraindicated for nirmatrelvir/ritonavir. This retrospective cohort study aimed to describe characteristics of patients offered

CONCLUSIONS: A variety of natural products, such as flavonoids, terpenoids, phenols, and alkaloids, were identified, which could be used as potential SASR-Cov-2 inhibitors. These shed new light on the efficient discovery of SASR-Cov-2 inhibitors from

INTRODUCTION: Exposure to secondhand smoke (SHS) is an established causal risk factor for cardiovascular disease (CVD) and chronic lung disease. Numerous studies have evaluated the role of tobacco in COVID-19 infection, severity, and mortality but

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CONCLUSION: Patients with CRF had higher risk of severe/critical COVID-19 than the general population. COVID-19 infection was associated with excess one-year mortality.

新型冠状病毒感染（coronavirus disease 2019，COVID-19）是由2型严重急性呼吸综合征冠状病毒（severe acute respiratory syndrome coronavirus 2，SARS-CoV-2）引起的疾病。COVID-19的临床症状多样，其中患者出现味觉障碍的报道越来越多。本文回顾了现有的国内外相关文献，对COVID-19患者味觉障碍的流行病学、潜在机制及治疗方式进行系统性归纳总结。味觉障碍的致病机制假说较多，具体机制尚不明确。目前缺乏有效的治疗方法

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The plans for a new antimicrobial utilization and resistance national surveillance programme, alongside the development of quality measures and methods to monitor unintended outcomes of antimicrobial stewardship and both public and professional

Identifying risk factors associated with COVID-19 lethality is crucial in combating the ongoing pandemic. In this study, we developed lethality predictive models for each epidemiological wave and for the overall dataset using the Extreme Gradient