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PubMed COVID-19 Clinical Care

1501 - 1510 of 2157 results found

Rise of the RNA machines - self-amplification in mRNA vaccine design

Date
Friday, June 16, 2023 - 4:00 AM
Description
mRNA vaccines have won the race for early COVID-19 vaccine approval, yet improvements are necessary to retain this leading role in combating infectious diseases. A next generation of self-amplifying mRNAs, also known as replicons, form an ideal

RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles

Date
Thursday, June 15, 2023 - 4:00 AM
Description
SARS-CoV-2 depends on host proteins for successful replication. In this issue, Williams et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202203060) report that the ER membrane-modulating proteins RTN3 and RTN4 are required for the formation of