PubMed COVID-19 Clinical Care
4081 - 4090 of 4656 results found
The Functional RNA Identification (FRID) Pipeline: Identification of Potential Pseudoknot-Containing RNA Elements as Therapeutic Targets for SARS-CoV-2
Description
The COVID-19 pandemic persists despite the development of effective vaccines. As such, it remains crucial to identify new targets for antiviral therapies. The causative virus of COVID-19, SARS-CoV-2, is a positive-sense RNA virus with RNA structures
The impact of preexisting psychiatric disorders and antidepressant use on COVID-19 related outcomes: a multicenter study
Description
Pre-existing mental disorders are linked to COVID-19-related outcomes. However, the findings are inconsistent and a thorough analysis of a broader spectrum of outcomes such as COVID-19 infection severity, morbidity, and mortality is required. We
The importance of appropriate selection of clinical endpoints in outpatient COVID-19 clinical trials
Description
Clinical trial endpoints must be carefully and intentionally selected so that the results of the trial can be used to inform policy- and decision-making. The relative importance of potential endpoints often depends on the stakeholder, with patients
Two case reports and a literature review of typical GBS and rare GBS variants associated with COVID-19
Description
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019, and is the infectious agent that caused the coronavirus disease 2019 (COVID-19) pandemic. Although respiratory and gastrointestinal manifestations of SARS-CoV-2 are
The health burden of natural and technological disasters in Brazil from 2013 to 2021
Description
Disasters deeply impact the health of the affected population and the economy of a country. The health burden of disasters in Brazil is underestimated and more studies are needed to underpin policies and actions for disaster risk reduction. This
The ongoing impact of COVID-19 on testing for and diagnoses of HIV and bacterial sexually transmitted infections in Oregon
Description
CONCLUSIONS: By 12/2021, HIV/STI testing had not recovered to pre-COVID-19 levels and HIV/STI continue to be underdiagnosed. Despite decreased testing, P&S syphilis cases have increased substantially.
The Palestinian primary ciliary dyskinesia population: first results of the diagnostic and genetic spectrum
Description
CONCLUSIONS: Despite limited local resources in Palestine, detailed geno- and phenotyping forms the basis of one of the largest national PCD populations globally. There was notable familial homozygosity within the context of significant population
Temporal dynamics and fatality of SARS-CoV-2 variants in Bangladesh
Description
CONCLUSION: Our findings highlight the importance of genomic surveillance for careful monitoring of variants of concern emergence to interpret correctly their relative IFR and CFR, and thus, for implementation of strengthened public health and social
The impact of a two-year long COVID-19 public health restriction program on mechanical thrombectomy outcomes in a stroke network
Description
CONCLUSIONS: COVID-19 pandemic has had a measurable impact on our mechanical thrombectomy program. Results showed similarities to other reported Latin American series, where less robust health systems could adapt less efficiently compared to