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PubMed COVID-19 Clinical Care

10291 - 10300 of 44782 results found

Effects of PEG antibodies on in vivo performance of LNP-mRNA vaccines

Date
Monday, December 11, 2023 - 4:00 AM
Description
Polyethylene glycol (PEG) plays important roles in stabilizing and lengthening circulation time of lipid nanoparticle (LNP) vaccines. Nowadays various levels of PEG antibodies have been detected in human blood, but the impact and mechanism of PEG

Peroxides Derivatives as SARS-CoV-2 Entry Inhibitors

Date
Monday, December 11, 2023 - 4:00 AM
Description
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Host cell invasion is mediated by the interaction of the viral spike protein (S) with human angiotensin-converting

Bile acids and bile acid activated receptors in the treatment of Covid-19

Date
Monday, December 11, 2023 - 4:00 AM
Description
Since its first outbreak in 2020, the pandemic caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has caused the death of almost 7 million people worldwide. Vaccines have been fundamental in disease prevention and to reduce

Comparative analysis of SARS-CoV-2 variants Alpha (B.1.1.7), Gamma (P.1), Zeta (P.2) and Delta (B.1.617.2) in Vero-E6 cells: ultrastructural characterization of cytopathology and replication kinetics

Date
Monday, December 11, 2023 - 4:00 AM
Description
This study compares the effects of virus-cell interactions among SARS-CoV-2 variants of concern (VOCs) isolated in Brazil in 2021, hypothesizing a correlation between cellular alterations and mortality and between viral load and transmissibility. For