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PubMed COVID-19 Clinical Care

3481 - 3490 of 44782 results found

Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant

Date
Thursday, February 08, 2024 - 4:00 AM
Description
Circulation of SARS-CoV-2 Omicron XBB has resulted in the emergence of XBB.1.5, a new Variant of Interest. Our phylogenetic analysis suggests that XBB.1.5 evolved from XBB.1 by acquiring the S486P spike (S) mutation, subsequent to the acquisition of

The scientific journey of a novel adjuvant (AS37) from bench to bedside

Date
Thursday, February 08, 2024 - 4:00 AM
Description
A decade ago, we described a new approach to discover next generation adjuvants, identifying small-molecule immune potentiators (SMIPs) as Toll-like receptor (TLR)7 agonists. We also optimally formulated these drugs through adsorption to aluminum