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PubMed COVID-19 Clinical Care

34851 - 34860 of 44782 results found

FAIR in action - a flexible framework to guide FAIRification

Date
Friday, May 19, 2023 - 4:00 AM
Description
The COVID-19 pandemic has highlighted the need for FAIR (Findable, Accessible, Interoperable, and Reusable) data more than any other scientific challenge to date. We developed a flexible, multi-level, domain-agnostic FAIRification framework

PARNAS: Objectively Selecting the Most Representative Taxa on a Phylogeny

Date
Friday, May 19, 2023 - 4:00 AM
Description
The use of next-generation sequencing technology has enabled phylogenetic studies with hundreds of thousands of taxa. Such large-scale phylogenies have become a critical component in genomic epidemiology in pathogens such as SARS-CoV-2 and influenza

Cycle threshold predicted mortality in a cohort of patients with hematologic malignancies infected with SARS-CoV-2

Date
Friday, May 19, 2023 - 4:00 AM
Description
When a SARS-CoV-2 RT-qPCR test is performed, it may determine an indirect measure of viral load called cycle threshold (Ct). Respiratory samples with Ct <25.0 cycles are considered to contain a high viral load. We aimed to determine whether SARS-CoV-2 Ct at diagnosis could predict mortality in patients with hematologic malignancies (lymphomas, leukemias, multiple myeloma) who contracted COVID-19. We included 35 adults with COVID-19 confirmed by RT-qPCR performed at diagnosis. We evaluated...